Vinayaka Mission University
Vinayaka Missions University (VMU) is a pioneering and vibrant school offering a multi-social experience with an atmosphere checked by the ideal congruity of living in differing qualities.
Years1
UNIT - 01
PROGRAMMING - PROGRAMME IN C-POINTERS TO FUNCTIONS - MACRO AND
PROGRAMMING IN C-GRAPHS - FILE AND EXCEPTION HANDLING IN C.
UNIT - 02
DATA STRUCTURE LINKED LIST - STACK - QUEUE - BINARY - TREES - THREATED BINARY
TREES.
UNIT - 03
VISUAL BASIC - PROGRAMMING VISUAL BASIC - INTRODUCTION TO APPLICATION
DEVELOPMENT USING VISUAL BASIC - WORKING WITH CODE AND FORMS.
UNIT - 04
DATA CONTROL - PROCEDURES AND CONTROLLING PROGRAMME EXECUTOR -
STANDARD CONTROLS - DATA ACCESS DATA CONTROL - CONNECTING TO DATABASE.
UNIT - 05
DATA WARE HOUSING - DATA CAPTURE - DATA ANALYSIS - DATABASE SIMILARITY
SEARCHES.
UNIT - 06
NUCLEIC ACID SEQUENCE DATA BANKS - INTRODUCTION - GENE BANK - EMBL
NUCLEOTIDE
SEQUENCE DATA BANK - AIDS VIRUS SEQUENCE DATA BANK - RRNA DATA BANK.
UNIT - 07
PROTEIN SEQUENCE DATA BANKS - INTRODUCTION - NBRF - PIR - SWISSPORT - SIGNAL
PEPTIDE DATA BANK.
UNIT - 08
ALGORITHMS - BLAST - FASTA - PSI - BLAST ALGORITHMS - PAIR WISE SEQUENCE
ALIGNMENT - NEEDLEMAN AND WUNSCH - SMITH WATERMAN ALGORITHMS.
UNIT - 09
ALIGNMENTS - MULTIPLE SEQUENCES ALIGNMENTS - CLUSTAL PRAS - PATTERNS -
MOTIFS AND PROFILES IN SEQUENCES - DERIVATION AND SEARCHING.
Vinayaka Missions University,Directorate of Distance Education
Salem India
MASTER OF SCIENCE IN BIO INFORMATICS
1 Yr.
BIOLOGICAL SEQUENCE ANALYSIS & STRUCTURAL
BIOLOGY(2030801)
UNIT - 10
DERIVED DATABASES OF PATTERNS - MOTIFS AND PROFILES - PROSITE - BLOCKS -
PRINTS-S-PFAM - PRIMER DESIGN.
UNIT - 11
ANALYSIS - ANALYSIS OF PROTEIN AND NUCLEIC AND SEQUENCES - MULTIPLE
ALIGNMENT PROGRAMS - DEVELOPMENT OF PROGRAMS FOR ANALYSIS OF NUCLEIC
AND SEQUENCES.
UNIT - 12
PACKAGE - USE OF GCG PACKAGE - CONVERSION OF VARIOUS FILE FORMATS - USE OF
MOLECULES MODELING PACKAGE(S) - PROGRAMS TO CALCULATE POTENTIAL ENERGY
OF REGULAR STRUCTURES AND THEIR VISUALIZATION - USE OF CURVE - NUPARM -
NEW HELIX.
A. BIOLOGICAL DATABANKS AND SEQUENCE ANALYSIS:
1.BIOLOGICAL DATABANKS SEQUENCE DATABASES, STRUCTURE DATABASES,
SPECIALIZED
2.DATABASES
3.DATA RETRIEVAL TOOLS AND METHODS
4.DATABASE FILE FORMATS
5.MOLECULAR VISUALIZATION
6.GENE STRUCTURE AND FUNCTION PREDICTION (USING GENSCAN, GENEMARK)
7.SEQUENCE SIMILARITY SEARCHING (NCBI BLAST)
8.PROTEIN SEQUENCE ANALYSIS (EXPASY PROTEOMICS TOOLS)
9.MULTIPLE SEQUENCE ALIGNMENT (CLUSTAL)
10.MOLECULAR PHYLOGENY PHYLIP
11.ANALYSIS OF PROTEIN AND NUCLEIC ACIDS SEQUENCES,
12.SEQUENCE ANALYSIS USING EMBOSS OR GCG WISCONSIN PACKAGE
B. COMPUTER PROGRAMMING:
I. PROGRAMMING IN C AND PERL:
I. CHARACTER ARRAY MANIPULATIONS
1) READ AND DISPLAY A CHARACTER ARRAY
2) REVERSE PRINT THE ARRAY (STING REVERSE)
3) LENGTH OF THE ARRAY
4) COPYING THE CONTENTS OF ONE ARRAY TO ANOTHER (STRING COPY)
5) COPY THE UPPERCASE CHARACTER OF ONE ARRAY AS LOWERCASE CHARACTER TO
ANOTHER
ARRAY
6) CHECKING WHETHER A STRING IS A PALINDROME OR NOT
7) COPY THE LEFT `N` CHARACTERS OF ONE ARRAY TO ANOTHER
8) COPY THE LAST `N` CHARACTERS OF ONE ARRAY TO ANOTHER
9) COPY THE MIDDLE `N` CHARACTERS OF ONE ARRAY TO ANOTHER
10) CONCATENATE TWO CHARACTER ARRAYS (STRING CONCATENATE)
11) COUNTING THE NUMBERS OF WORDS, LINES AND CHARACTERS IN AN ARRAY
12) COUNTING THE NUMBERS OF UPPERCASE AND LOWERCASE ALPHABETS, DIGITS
AND
SPECIAL CHARACTERS IN AN ARRAY
13) CHECK THE NUMBER OF OCCURRENCES OF A PATTERN
14) CHECK THE OCCURRENCES OF A PATTERN AND SKIP THE SAME.
15) CHECK THE OCCURRENCES OF A PATTERN AND REPLACE IT WITH A DIFFERENT
PATTERN
BIOLOGICAL SEQUENCE ANALYSIS & STRUCTURAL BIOLOGY JAVA
LAB(2030802)
II. POINTERS AND CHARACTER ARRAY
16) PATTERN COUNTING
17) PATTERN SKIPPING
18) PATTERN REPLACING
III. FILES AND COMMAND LINE ARGUMENTS
19) READ DATA FROM THE KEYBOARD AND WRITE IT IN THE FILE(CHAR BY CHAR)
20) READ DATA FROM THE FILE AND DISPLAY IT ON THE SCREEN(CHAR BY CHAR)
21) DISPLAY THE CONTENT OF ALL THE FILES(CAT ALL THE FILES)
22) COPY DATA FROM ONE FILE TO ANOTHER
23) PATTERN COUNT
24) LINE IN WHICH THE PATTERN OCCURS WITH LINE NUMBER
25) GREP ALL FILES (PATTERN MATCH ALL THE FILES)
ANX.45 B - M.SC BIOINF (CBCS) 2007-08 PAGE 20 OF 29
II. PERL PROGRAMMING:
1. PROGRAM TO STORE A DNA SEQUENCE
2. PROGRAM TO CONCATENATE DNA FRAGMENTS
3. PROGRAM TO CONVERT DNA TO RNA
4. PROGRAM TO CALCULATE REVERSE COMPLIMENT OF DNA SEQUENCE
5. PROGRAM TO READ PROTEIN SEQUENCE DATA FROM A FILE
6. PROGRAM TO PRINT THE ELEMENTS OF A ARRAY
7. PROGRAM TO TAKE AN ELEMENT OFF THE END OF AN ARRAY
8. PROGRAM TO TAKE AN ELEMENT OFF THE BEGINNING OF AN ARRAY
9. PROGRAM TO PUT AN ELEMENT AT THE BEGINNING OF AN ARRAY
10. PROGRAM TO PUT AN ELEMENT AT THE END OF AN ARRAY
11. PROGRAM TO REVERSE AN ARRAY
12. PROGRAM TO GET THE LENGTH OF AN ARRAY
13. PROGRAM TO INSERT AN ELEMENT AT A RANDOM POSITION IN AN ARRAY
14. PROGRAM TO FIND MOTIFS IN A PROTEIN SEQUENCE
15. PROGRAM TO COUNT NUCLEOTIDES IN A SEQUENCE
16 PROGRAM TO FIND THE PERCENTAGE OF HYDROPHOBIC AMINO ACIDS IN A
SEQUENCE
BIOLOGY OF CELLS - CELLS AS A UNIT OF LIFE - STRUCTURE OF PROKAYOTIC AND
EUKARYOTIC CELLS - AN OVERVIEW OF ORGANELLS (MITOCHONDRIA, CHLOROPLASTS,
ER, GOLGI, RIBOSOMES, LYSOSOMES AND PEROXYSOMES, NUCLEUS AND NUCLEOLUS)
- DIFFERENCES AND SIMILARITIES IN PLANT AND ANIMAL CELLS - CELLULAR MEMBRANE
- STRUCTURE - TRANSPORT - CHANNELS - CARRIERS - RECEPTORS - ENDOCYTOSIS -
MEMBRANE POTENTIALS.
DNA REPLICATION - TRANSCRIPTION AND TRANSLATION - CELL-CELL INTERACTIONS
AND SIGNAL TRANSDUCTIONS: INTERCELLULAR JUNCTIONS - SIGNALING BY
HORMONES AND NEUROTRANSMITTERS.
DNA REPAIR - CHROMOSOMAL TYPES AND STRUCTURE - MECHANISM BY WHICH
GENOME UNDERGOES CHANGES - RECOMBINATION - MUTATION - INVERSION -
DUPLICATION AND TRANSPOSITION.
CELL CYCLE AND REGULATION - MITOSIS - MEIOSIS - MUTATION - TYPES OF MUTATIONS
- TYPES OF MUTAGENIC AGENTS AND THEIR MOLECULAR MECHANISM.
BACTERIAE - EUBACTERIA - CYANOBACTERIA - ARCHAEBACTERIA - BERGEY`S
CLASSIFICATION SCHEME FOR BACTERIA.
STAINING OF BACTERIA - SIZE AND SHAPE OF BACTERIAL CELLS - MODES OF
REPRODUCTION - ENUMERATION - BACTERIAL GROWTH CURVE - SYNCHRONOUS
GROWTH - PHYSICAL AND CHEMICAL METHODS OF CONTROLLING BACTERIAL GROWTH
- CULTIVATION OF BACTERIA - NUTRITIONAL REQUIREMENTS - TYPES OF MEDIA -
FACTORS AFFECTING GROWTH - CHOICE OF MEDIA AND CONDITIONS OF INCUBATION -
ISOLATION AND MAINTENANCE OF PURE CULTURES.
FUNGI ALGAE AND VIRUSES - FUNGI - CLASSIFICATION - CULTIVATION AND
MORPHOLOGY OF YEASTS AND MOLDS - CONTROL OF FUNGAL GROWTH - ALGAE -
OCCURRENCE - CHARACTERISTICS - CLASSIFICATION AND BIOLOGICAL - IMPORTANCE -
VIRUSES OF BACTERIA - BACTERIOPHAGES - GENERAL CHARACTERISTICS.
CELL & MOLECULAR BIOLOGY, MICROBIOLOGY &
IMMUNOLOGY(2060104)
IMMUNOLOGY - THE IMMUNE SYSTEM - INTRODUCTION: PRIMARY AND SECONDARY
LYMPHODOIL ORGAN - LYMPHOCYTES - THEIR ORIGIN AND DIFFERENTIATION -
ANTIGEN PRESENTING CELLS - MACROPHAGES - DENDRITIC CELLS - LANGERHANS
CELL - THEIR ORIGIN AND FUNCTION.
MECHANISM OF PHAGOCYTOSIS - IDENTIFICATION OF CELL TYPES OF IMMUNE SYSTEM
- COMPLEMENT AND THEIR BIOLOGICAL FUNCTION - TYPES OF IMMUNE RESPONSES -
IMMUNE TOLERANCE - BLOOD GROUP ANTIGENS
TYPES AND CHARACTERISTICS OF ANTIGEN - ANTIGEN - ANTIBODY INTERACTIONS -
ANTITOXINS - AGGLUTINATION - OPSONIN - BACTERIOLYSIN AND PRECIPITATION.
IMMUNITY - TYPES OF IMMUNITY - INNATE IMMUNITY - SURFACE BARRIERS
PHAGOCYTOSIS - ACQUIRED
IMMUNITY - ACTIVE AND PASSIVE - ANTITOXIC - ANTIBACTERIAL AND ANTIVIRAL
IMMUNITY.
IMMUNOCHEMICAL TECHNIQUES - PRODUCTION OF ANTISERA - THE PRECIPITATION
REACTION - IMMUNODIFFUSION - IMMUNOELECTROPHORESIS -
IMMUNOFLUORESCENCE - COMPLIMENT FIXATION - PRINCIPLE - TECHNIQUE AND
APPLICATIONS OF RIA AND ELISA.
CHEMISTRY OF WATER - PH - BUFFERS - CELL ORGANELLES - STRUCTURE AND
FUNCTIONS OF CELL ORGANELLES - TRANSPORT MECHANISM - ION CHANNELS -
MEMBRANE PERMEABILITY.
STRUCTURE - PROPERTIES AND FUNCTIONS OF CARBOHYDRATES - LIPIDS - PROTEIN
AND NUCLEIC ACIDS.
ENZYMOLOGY 1 - CLASSIFICATION - CO ENZYMES - STRUCTURE AND MODE OF ACTION
OF ENZYMES.
ENZYMOLOGY 2 - ACTIVE CENTRE - KINETICS - MICHALIS CONSTANT.
ENZYMOLOGY 3 - INHIBITION - COVALENT MODIFICATION - CATALYSIS - ACTIVE
REPRESSION - INDUCTION.
ENZYMOLOGY 4 - ISO ENZYMES - IMMOBILIZED ENZYMES - DIAGNOSTIC USES OF
ENZYMES.
METABOLISM - CARBOHYDRATE - PROTEIN - LIPIDS AND NUCLECIC ACIDS.
VITAMINS - DEFINITION - CLASSIFICATION - SOURCES - FUNCTIONS - DEFICIENCY -
SYMPTOMS OF FAT SOLUBLE AND WATER SOLUBLE VITAMINS.
MOLECULAR BIOLOGY - DNA STRUCTURE - REPLICATION - TRANSCRIPTION AND
TRANSLATION.
GENETIC CODE - POST TRANSCRIPTIONAL AND POST TRANSLATIONAL MODIFICATION.
MUTATION - TYPES OF MUTATION - USES OF MUTATIONS - DNA DAMAGE -
RECOMBINANT DNA TECHNOLOGY.
BIOSENSORS - DEFINITION - TYPES - USAGE IN BIOCHEMISTRY -BLOTTING TECHNIQUES
- PCR (POLYMERASE CHAIN REACTION) AND RFLP (RESTRICTION FRAGMENT LENGTH
POLYMORPHISM).
ELEMENTS OF BIO CHEMISTRY(2030704)
FUNDAMENTALS OF COMPUTING - INTRODUCTION TO OPERATION SYSTEMS -
WINDOWS NT UNIX - LINUX OPERATING SYSTEMS - COMPARATIVE ADVANTAGES OF
SECURITY (HACKING - CRACKING) - INSTALLATION - PORTABILITY AND PROGRAMMING
OF THESE OPERATING SYSTEMS
COMPUTER VIRUSES - USE OF INTERNET - WWW. SEARCHES ON MEDICINE - CD -
BIBLIOGRAPHIC DATABASES
GRAPHICS - VISUALIZATION TECHNIQUES - SOFTWARE AND HARDWARE - INTERACTIVE
GRAPHICS VIEWING IN THREE DIMENSIONS
RASTER ALGORITHMS - SURFACE AND SOLID MODELING - RENDERING - ANIMATION -
IMAGE PROCESSING WITH STRESS ON BIOLOGICAL SYSTEMS - 3-D IMAGE
RECONSTRUCTION
COMPUTER NETWORKING - LAN - WAN - MODEM - OPTICAL VS ELECTRONIC
NETWORKING SECURITY OF THE NETWORK - FIRE-WALLS - NETWORK GOALS -
APPLICATIONS NETWORK
NETWORK STURCTURE - NETWORK ARCHITECTURE - HIERARCHICAL NETWORKS -
ETHERNET AND TCP/IP - FAMILY OF PROTOCOLS - TRANSPORT PROTOCOL DESIGN
PRACTICAL - EXERCISES ON WINDOWS - LINUX - UNIX NETWORKING - INTERNET
SEARCH AND GRAPHICS
CALCULUS - LIMITS - COMPLETE DIFFERENTIALS - PARTIAL DIFFERENTIAL OF
FUNCTIONS - INTEGRATION - DEFINITE AND NON-DEFINITE INTEGRAL - LOGARITHMS -
ORDINARY DIFFERENTIAL EQUATIONS (FIRST ORDER) - PARTIAL DIFFERENT
EQUATIONS - EXAMPLE FROM BIOLOGY
VECTOR - ADDITIONS - SUBTRACTIONS - DOT - CROSS - SCALAR TRIPLE PRODUCT -
DIVERGENCE CURL OF A VECTOR - EQUATION NORMAL - MATYRIX ALGEBRA - ADDITION
- SUBTRACTION - MULTIPLICATION - TRANSPOSE INVERSE AND CONJUGATE OF MATRIX
BOOLEAN LOGIC - ADDITION - SUBTRACTION - MULTIPLICATION AND DIVISION USING
BINARY - OCTAL AND HEXADECIMAL SYSTEMS
JAVA/BIO-JAVA, BIO-STATISTICS(2050206)
INTRODUCTION TO PRINCIPLE OF STATISTICAL SAMPLING FROM A POPULATION -
RANDOM SAMPLING
FREQUENCY DISTRIBUTIONS AND ASSOCIATED STATISTICAL MEASURES - PROBABILITY
DISTRIBUTIONS - CORRELATION AND REGRESSION ANALYSIS
MULTIVARIATE ANALYSIS - HYPOTHESIS TESTING - MARKOV MODELS - CLUSTER
ANALYSIS - NEAREST NEIGHBORS SEARCH. SEARCH USING STEM NUMBERS - SEARCH
SING TEXT SIGNATURES - PHYLOGENETIC ANALYSIS TOOLS - MAXIMUM LIKELIHOOD -
PARSIMONY METHODS
AMINO ACID - INTRODUCTION - DEFINITION - STRUCTURE - PROPERTIES -
CLASSIFICATION OF AMINO ACID.
MUTATION - INTRODUCTION - DEFINITION - EFFECT OF MUTATION IN AMINO ACIDS
SUBSTITUTION.
STRUCTURE OF PROTEIN - STRUCTURAL CLASSIFICATION OF PROTEIN - PRIMARY -
SECONDARY - TERTIARY - QUATERNARY STRUCTURE.
PROPERTIES OF PROTEINS - PROTEIN FOLDING AND DEFOLDING PROCESSES.
PROTEIN SYNTHESIS - RNA TYPES - GENETIC CODES OF DIFFERENT AMINO ACIDS -
TRIPLE LET CODE - H.L. KHOVAN`S WOVK.
MOLECULAR MODELING - PROTEIN ENGINEERING IN INVITRO AND INVIVO CONDITIONS.
MECHANISM OF PROTEIN - MECHANISM OF PROTEIN DESIGNING IN PHARMACO
PROTEOMICS.
APPLICATIONS OF PROTEIN - APPLICATIONS OF PROTEIN ENGINEERING AND PROTEIN
FOLDING.
TECHNIQUES IN PROTEIN - TECHNIQUES IN PROTEIN STRUCTURE AND FUNCTIONAL
ANALYSIS.
SPECTROSCOPY - NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY (NMR) - -RAY -
MASS SPECTROSCOPY - MALDI MASS SPECTROMETER.
MASS SPECTROMETER - Q-TOF MASS SPECTROMETER - 2-D GEL PEPTIDE SEQUENCING
- CURRENT STATUS OF PROTEIN ENGINEERING.
BLOTTING TECHNIQUES - RAMACHANDRAN BLOT - WESTERN BLOTTING.
PROTEIN ENGINEERING(203080MSC(BIO-INFOR) 2 Yr.
Years2
GENOME - OVERVIEW OF GENOME; SEQUENCE OF GENOME ACQUSITION AND
ANALYSIS - HOMOLOGIES - SNPS - GENETIC ANALYSIS, LINKAGE MAPPING, HIGH
RESOLUTION CHROMOSOME MAPPING AND ANALYSIS - PHYSICAL MAPPING, YAC,
HYBRID MAPPING, STRATEGIES, SEQUENCE SPECIFIC TAGS (SST), SEQUENCE TAGGED
SITES(STS), ISH, FISH, RFLP, RAPD.
DNA SEQUENCING - MDTHODS, MAXAM AND GILBERT METHOD, LADDER,
FLOURESCENT, SHOT GUN, MASS SPECTROMETRY, AUTOMATION DEQUENCING - FIND
GENE MUTATIONS, IMPLICATIONS OF DNA - SEQUENCING AND SEQUENING GENOMES.
GENOME DATA BANK, METABOLIC PATHWAY DATA - CONSTRUCTION AND SCREENING
OF CDNA, LIBRARIES AND MICROARRAYS - PPLICATION OF DNA ARRAYS - PCR -
VARIATIONS IN PCR - GENE DISTRUPTIONS - SAGE AND SADE, PHARMACOGENOMICS.
PROTEIN SEQUENCE ANALYSIS - INTRODUCTION - SEQUENCE DATA BANKS - WBRF - PIR
- SWISSPORT - DATABASES, DATA MINING - ALGORITHMS OF PROTEOMICS AND ITS
APPLICATIONS - PROTEIN EXPRESSION PROFILLING - PROTEIN - PROTEIN INTERACTION
- PROTEIN MODIFICATIONS. AUTOMATION - NUCLEIC ACID DATA BANK - EMBL
NUCLEOTIDE SEQUENCE DATA BANK - AIDS VIRUS SEQUENCE DATA BANK - RNA DATA
BANK.
TOOLS FOR DATA BANK - PAIRWISE ALIGNMENT - NEEDLEMAN AND WUSCH ALGORIGHM
- SMITH WATERMAN - MULTIPLE ALIGNMENT - CLUSTRAL - PRAS - BLAST - FAST,
ALGORITHMS TO ANALYSE SEQUENCE DATA - PDB, CAMBRIDGE STRUCTURE DATA
BASE (LSD), 2D ELECTROPHORESIS, IEF, HPLC, PROTEIN DIGESTION TECHNIQUE, MASS
SPECTROMETRY, MALDI, TOF, PEPTIDES, MASS FINGER, PRINTING, PROTEIN.
2 Yr.
GENOMICS AND PROTEOMICS(2030902)
INTRODUCTION TO THE CONCEPTS OF MOLECULAR MODELLING - MOLECULAR
STRUCTURE AND INTERNAL ENERGY - APPLICATION OF MOLECULAR GRAPHICS -
ENERGY MINIMISATION OF SMALL MOLECULES. EMPRICAL RESPRESENTATION OF
MOLECULAR ENERGIES USE OF FORCE FIELDS AND THE MOLECULAR MECHANISM
METHODS. DISCUSSION OF LOCAL AND GLOBAL ENERGY MINIMA.
TECHNIQUES OF MOLECULAR DYNAMICS - AND MONTE-CARLO SIMULATIONS FOR
CONFIRONATIONAL ANALYSIS - AB INITIO DFT AND SEMI EMBRICAL METHODS -
QUANTUM MECHANICAL MODELS.
MACROMOLECULAR MODELLING - DESIGN OF GIAND FOR KNOWN MACROMOLECULAR
TARGET SITES - DRUG RECEPTOR INFERACTION - DRUG ACTIONS NOT MEDIATED BY
RECEPTORS - SAR/QSAR STUDIES AND THEIR INPLICATIONS TO THE 3-D MODELLER -
2D, 3D DATABASE SEARCHING - PHARMACOPHONE IDENTIFICATION AND NOEL DRUG
DESIGN.
BIODIVERSITY OF PLANTS AND ANIMALS - MORPHOLOGICAL CLASSIFICATION OF
PLANTS - VARIOUS SYSTEM, BINOMIAL NOMENCLATURE, CYTOTAXONOMY,
CHEMOTAXONOMY, MORPHOLOGICAL CLASSIFICATION OF ANIMALS - ANIMAL
DIVERSITY, CLASSIFICATION OF CHORDATES AND NON-CHORDATES, UPTO CLASSES.
ORIGIN AND PHYLOGENY OF LIFE - FOSSILS, DATING FOSSILS, GEOLOGICAL TIME
SCALE, LAMARKISM, NEOLAMARKISM, LIVING FOSSILS - MODERN CONCEPTS OF
EVOLUTION AND SPECIATION, VARIATION, NATURAL SELECTION, ISOLATION,
MECHANISM IN EVOLUTION AND SPECIATION.
MOLECULAR MODELLING AND BIO DIVERSITY
INFORMATICS(2030903)
ERRORS IN MODELING - ERRORS INVOLVED IN THE CONSTRUCTION OF A
MATHEMATICAL MODEL OF THE REAL PHYSICAL PROCESS - ERRORS IN NUMERICAL
CALCULATIONS - ERRORS IN THE NUMERICAL APPROXIMATION OF THE MATHEMATICAL
MODEL (TRUNCATION ERRORS) - ERRORS IN A SERIES APPROXIMATION - ERRORS IN
THE ACTUAL COMPUTATION USING A COMPUTER (ROUND OFF ERRORS).
MINIMIZATION OR MAXIMATION OF FUNCTION PROBLEMS WITH MINIMUM NUMBER OF
ITERATIONS - ONE- DIMENSIONAL OPTIMIZATION - GOLDEN SECTION METHOD -
PARABOLIC INTERPOLATION AND BRENT`S METHOD IN ONE DIMENSION - ONEDIMENSIONAL
SEARCH WITH FIRST DERIVATIVES SECONDORDER DERIVATIVE -
NEWTON - RAPHSON METHOD.
MULTIDIMENSIONAL OPTIMIZATION - UNIVARIATE METHOD - PATTERN DIRECTIONS -
POWELL`S METHOD - CONJUAGATE DIRECTIONS - ALGORITHM - QUADRATIC
CONVERGENCE - DOWNHILL SIMPLEX METHOD IN MULTI DIMENSIONS - INDIRECT
SEARCH METHODS - GRADIENT - STEEPEST DECENT (CAUCHY) METHOD - CONJUGATE
GRADIENT (FLETCHER - REEVES) METHOD - PROCEDURE.
RANDOMIZED MINIMIZATION TECHNIQUES - MONTE - CARLO MINIMIZATION - GENETIC
ALGORITHMS - REPRESENTATION OF DESIGN VARIABLES - REPRESENTATION OF
OBJECTIVE - FUNCTION AND CONSTRAINTS - GENETIC OPERATORS - SIMULATED
ANNEALING - PROCEDURE - FEATURES.
FOURIER TRANSFORM - FOURIER TRANSFORM OF DISCRETELY SAMPLED DATA -
DISCRETE CONVOLUTION - PERIODIC SEQUENCE AND CIRCULAR CONVOLUTION -
LINEAR CONVOLUTION THROUGH CIRCULAR CONVOLUTION - FAST FOURIER
TRANSFORM(FFT) - DISCRETE IN TIME(DIT) - DISCRETE IN FREQUENCY(DIF) -
ALGORITHM - COMPUTATION OF INVERSE DFT - SIMPLE PROBLEMS.
NUMERICAL SOLUTIONS OF ODES SOLUTION BY TAYLOR`S SERIES METHOD - EULER`S
METHOD - MODIFIED EULER METHOD - MIDPOINT METHOD - RUNGE - KUTTA METHOD -
PREDICTOR -CORRECTOR METHODS
ADAM`S - MOULTON METHOD - MILNE`S METHOD - SIMULTANEOUS AND HIGHER ORDER
EQUATIONS - METHODS TO SOLVE STIFF EQUATIONS (IMPLICIT EULER METHOD AND
EXPLICIT EULER METHOD).
NUMERICAL METHODS AND OPTIMISATION TECHNIQUES(2030904)
CHEMICAL FOUNDATION OF BIOLOGY - PH - ACIDS - BUFFERS - WEAK BONDS -
COVALENT BONDS - PRINCIPLES OF THERMODYNAMICS - AMINO ACIDS AND PEPTIDES -
CLASSIFICATION - CHEMICAL REACTIONS AND PHYSICAL PROPERTIES - SUGARS -
CLASSIFICATION AND REACTIONS.
HETEROCYCLIC COMPOUNDS AND SECONDARY METABOLITES IN LIVING SYSTEM -
NUCLEOTIDES PIGMENTS - SEPERATION TECHNIQUES OF DIFFERENT BIOMOLECULES -
LIPIDS - CLASSIFICATION, STRUCTURE AND FUNCTIONS - PROTEINS AND NUCLEIC ACIS,
CLASSIFICATION, SEPERATION, PURIFICATION AND CRITERIA OF HOMOGENECITY AND
GROUP ANALYSIS.
POLYSACCHARIDE -TYPES, STRUCTURE, METHODS OF COMPOSITIONAL ANALYSIS,
ANALYTICAL TECHNIQUES IN BIOCHEMISTRY AND BIOPHYSICS FOR SMALL MOLECULE
AND MACRO MOLECULES.
COMMERCIAL ASPECTS OF BIOINFORMATICS - DRUG DESIGNING - STRUCTURE BASED
DRUG DESIGN - MECHANISM OF THEIR ENZYME INHIBITION STRATEGIES - STRUCTURE
OF COMMONLY USED DRUGS IN CLINICAL LABORATARY - FINDING NEW FORGETS TO
TREAT DISEASE - QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIP (QSAR).
PRINCIPLES OF CANCEROTHERAPY - TARGET SITES FOR CANCER
CHEMOTHERAPEUTIC AGENTS - MODE OF ACTION OF ANTICANCER DRUGS,
ANTIMETABOLITES - ANTIBODIES, ALKYLATING AGENTS, HORMONES AND THEIR
AGENTS - EFFECTS OF CHEMOTHERAPUTIC AGENTS ON THE GROWTH CYCLE OF
MAMMALIAN CELLS.
CHEMO INFORMATICS AND COMMERCIAL BIO INFORMATICS(2030905)
1. BIOLOGICAL DATABANKS - SEQUENCE DATABASE STRUCTURE DATABASE,
SPECIALSIED DATABASE.
2. DATA RETRIVAL TOOL AND METHOD.
3. DATABASE FILE FORMAT.
4. MOLECULAR VISUALIZATION.
5. GENE STRUCTURE AND FUNCTIONS PREDICTION (USING GENSCAN, GENE MARK).
6. PROTEIN SEQUENCE ANALYSIS (EXPASY PROTEOMICS METHOD)
7. MOLECULAR PHYSIOLOGY (PHYLIP)
8. ANALYSIS OF PROTEIN AND NUCLEIC ACID SEQUENCE USING EMBOSS (OR) GCG.
PRACTICAL I- DATA BASE SYSTEMS (M.SC BIO
INFORMATICS)(2030906)
1. PROGRAMME TO STORE A DNA-SEQUENCE.
2. PROGRAMME TO CONVERT DNA-RNA.
3. PROGRAMME TO CALCULATE REVERSE COMPLEMENT OF DNA SEQUENCE.
4. PROGRAMME TO READ PROTEIN SEQUENCE DATA FROM A FILE.
5. PROGRAMME TO PRINT THE ELEMENT OF A ARRAY.
6. PROGRAMME TO REVERSE AN ARRAY.
7. PROGRAMME TO GET THE LENGTH OF AN ARRAY.
8. PROGRAMME TO FIT MOTIF IN A PROTEIN SEQUENCE.
9. PROGRAMME TO COUNT NUCLEOSIDE IN A SEQUENCE.
10. PROGRAMME TO FIND PERCENTAGE OF G AND C IN A DNA SEQUENCE.
PRACTICAL III (BIO INFORMATICS)(2030907)
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